Flow cytometry detection of vitamin D receptor changes during vitamin D treatment in Crohn's disease
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چکیده
منابع مشابه
Vitamin D, vitamin D receptor and tissue barriers
Tissue barriers are critical in the pathogenesis of human diseases, such as atopic dermatitis, inflammatory bowel diseases, and various cancers. Preserving or restoring barrier functions of the epithelia cells is a therapeutic strategy to prevent and treat the illness. Mounting evidence indicates that vitamin D and the vitamin D receptor (VDR) play key roles in the pathogenesis of human disease...
متن کاملVitamin D Treatment Guidelines
Measurement of 25(OH)D in the circulation is the best diagnostic test for determining a person’s vitamin D status.1 Usually 1,25(OH)2D levels in the circulation are normal or elevated in vitamin D deficient patients and thus should not be used to determine a person’s vitamin D status. However, 1,25(OH)2D measurement is of value in acquired and inherited disorders of vitamin D metabolism includi...
متن کاملAssociation of vitamin D deficiency and premature coronary artery disease
Background: Evidence suggests hypovitaminosis D is associated with increased risk of coronary artery disease (CAD) and its extent and related risk factors. However, some investigations have produced contrary results. Therefore, we aimed to evaluate the association between serum vitamin D levels and the severity of premature coronary artery involvement. Methods: This randomized prospective, cas...
متن کاملStatus of Vitamin-D in diabetic patients
Abstract Background: Vitamin D (vit D) deficiency has been found to have an inverse relationship with the occurrence of type-2 diabetes mellitus (DM). The aim of this study was to assess the vit D level in type-2 diabetic patients. Methods: One hundred-twenty DM patients selected as case group and 120 healthy individuals as control group were investigated in this study from October 2011 to S...
متن کاملVitamin D receptor and analogs.
In chronic kidney disease (CKD), high circulating levels of parathyroid hormone (PTH) cause osteitis fibrosa, bone loss, and cardiovascular complications that increase morbidity and mortality. Impaired production of 1,25-dihydroxyvitamin D (calcitriol), the hormonal form of vitamin D, is a major contributor to the generation and maintenance of parathyroid hyperplasia and increased synthesis and...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2015
ISSN: 0009-9104,1365-2249
DOI: 10.1111/cei.12613